Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21424522 | 1.00 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL21424550 | 0.77 | CYP19A1 (0.47) | CYP19A1 | |
| SCHEMBL22811521 | 0.77 | CYP19A1 (0.47) | CYP19A1 | |
| SCHEMBL21424455 | 0.76 | CYP11B1 (0.35) | — | |
| SCHEMBL22811772 | 0.76 | CYP11B1 (0.35) | — | |
| SCHEMBL8763308 | 0.75 | ESR1 (0.34) | — | |
| SCHEMBL19003073 | 0.71 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL12303207 | 0.71 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL21424523 | 0.71 | HDAC8 (0.30) | — | |
| SCHEMBL22811544 | 0.71 | HDAC8 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541803-B1 | TRIAZOLE PYRIDYL COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2020-12-23 | — | — | EP | disclosed |