Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21424523 | 1.00 | HDAC8 (0.30) | HDAC8 | |
| SCHEMBL19663654 | 0.76 | — | — | |
| SCHEMBL21424522 | 0.71 | CYP19A1 (0.40) | — | |
| SCHEMBL22811534 | 0.71 | CYP19A1 (0.40) | — | |
| SCHEMBL12310230 | 0.69 | HRH1 (0.32) | — | |
| SCHEMBL28003526 | 0.69 | — | — | |
| SCHEMBL10544432 | 0.68 | HDAC8 (0.31) | HDAC8 | |
| SCHEMBL25209792 | 0.67 | — | — | |
| SCHEMBL24602914 | 0.67 | — | — | |
| SCHEMBL20733949 | 0.67 | HDAC8 (0.37) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541803-B1 | TRIAZOLE PYRIDYL COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2020-12-23 | — | — | EP | disclosed |