7'',4'''-Dimethylamentoflavone

7'',4'''-Dimethylamentoflavone

SCHEMBL30646161

COc1ccc(-c2cc(=O)c3c(O)cc(OC)c(-c4cc(-c5cc(=O)c6c(O)cc(O)cc6o5)ccc4O)c3o2)cc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.72
MEN1 O00255 4/20 0.70
KMT2A Q03164 4/20 0.70
CYP1B1 Q16678 4/20 0.70
MAPT P10636 3/20 0.70
CYP1A1 P04798 3/20 0.70
CYP1A2 P05177 3/20 0.70
IP6K2 Q9UHH9 3/20 0.70
ALDH1A1 P00352 2/20 0.70
USP2 O75604 2/20 0.70
TP53 P04637 2/20 0.70
MAOB P27338 2/20 0.70
TDP1 Q9NUW8 2/20 0.70
FLT3 P36888 2/20 0.70
NPC1 O15118 1/20 0.70
LMNA P02545 1/20 0.70
CYP3A4 P08684 1/20 0.70
CYP2D6 P10635 1/20 0.70
CYP2C9 P11712 1/20 0.70
KCNE1 P15382 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
7'',4'''-Dimethylamentoflavone SCHEMBL27350631 1.00 APP (0.72) APPMEN1KMT2ACYP1B1MAPT
Heveaflavone SCHEMBL27350698 0.96 APP (0.72) APPMEN1KMT2ACYP1B1MAPT
Heveaflavone SCHEMBL30646163 0.96 APP (0.72) APPMEN1KMT2ACYP1B1MAPT
Kayaflavone SCHEMBL27350697 0.94 MEN1 (0.71) APPMEN1KMT2ACYP1B1MAPT
Kayaflavone SCHEMBL30646162 0.94 MEN1 (0.71) APPMEN1KMT2ACYP1B1MAPT
Sotetsuflavone SCHEMBL4467051 0.94 APP (0.80) APPMEN1KMT2ACYP1B1MAPT
Sotetsuflavone SCHEMBL30646165 0.94 APP (0.80) APPMEN1KMT2ACYP1B1MAPT
Podocarpusflavone A SCHEMBL29496316 0.92 MEN1 (0.72) APPMEN1KMT2ACYP1B1MAPT
Podocarpusflavone A SCHEMBL25937932 0.92 MEN1 (0.72) APPMEN1KMT2ACYP1B1MAPT
SCHEMBL22459584 0.90 MAPT (0.77) APPMEN1KMT2ACYP1B1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228814-A1 COMBINATION THERAPIES FOR THE TREATMENT OF VIRAL INFECTIONS FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2025-07-17 US disclosed
WO-2023250111-A1 COMBINATION THERAPIES FOR THE TREATMENT OF VIRAL INFECTIONS FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2023-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228814-A1 COMBINATION THERAPIES FOR THE TREATMENT OF VIRAL INFECTIONS HAVCR2, EIF2AK2, MAVS APP 3207/4885MEN1 3073/4885KMT2A 3798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.