SCHEMBL228138

SCHEMBL228138

CC(C)(C)c1ccc(-c2c3c(c(-c4ccc(C(C)(C)C)cc4C(C)(C)C)c(-c4ccc(C(C)(C)C)cc4C(C)(C)C)c2-c2ccc(C(C)(C)C)cc2C(C)(C)C)-c2ccccc2-3)c(C(C)(C)C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
NPC1 O15118 3/20 0.53
RAB9A P51151 3/20 0.53
CASP3 P42574 2/20 0.53
SENP8 Q96LD8 2/20 0.53
SENP7 Q9BQF6 2/20 0.53
SENP6 Q9GZR1 2/20 0.53
PLA2G1B P04054 1/20 0.53
NFKB1 P19838 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ATG4B Q9Y4P1 1/20 0.53
KIF11 P52732 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
HPGD P15428 2/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
NR1H3 Q13133 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1903605 0.91 NPC1 (0.46) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL1902888 0.91 ALDH1A1 (0.49) ALDH1A1NPC1RAB9ACASP3SENP8
Phosphonic Acid SCHEMBL455332 0.90 ALDH1A1 (0.49) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL30285371 0.88 ALDH1A1 (0.44) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL12803214 0.88 ALDH1A1 (0.44) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL28326671 0.88 ALDH1A1 (0.57) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL5080714 0.88 ALDH1A1 (0.57) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL6027001 0.87 ALDH1A1 (0.42) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL29382727 0.87 ALDH1A1 (0.42) ALDH1A1NPC1RAB9ACASP3SENP8
SCHEMBL4920238 0.87 ALDH1A1 (0.49) ALDH1A1NPC1RAB9ACASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1010 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10268066-B2 Photosensitive resin composition, color conversion panel using the same and display device SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-23 US claimed
EP-2796495-B1 METHOD OF PRODUCING OLEFIN RESIN COMPOSITION ADEKA CORP (JP) 2018-07-04 EP claimed
US-20160202548-A1 PHOTOSENSITIVE RESIN COMPOSITION, COLOR CONVERSION PANEL USING THE SAME AND DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-14 US claimed
US-9133121-B2 Weakly basic hindered amines compounds having carbonate skeletons, synthetic resin compositions and coating compositions NEGISHI YOSHINORI (JP) 2015-09-15 US claimed
US-6593485-B1 Organic phosphite, mono- or diphosphonite compounds; acid scavenger, and 2,2,6,6-tetraalkylpiperidinyl group and sterically hindered antioxidant CLARIANT FINANCE (BVI) LIMITED (VG) 2003-07-15 US claimed
EP-0335198-B1 Ignition resistant moulded article and method for preparing the same DOW CHEMICAL CO (US) 1998-06-10 EP claimed
EP-0335198-A2 Ignition resistant moulded article and method for preparing the same THE DOW CHEMICAL COMPANY (US) 1989-10-04 EP claimed
US-4826900-A POLYTETRAFLUOROETHYLENE, DRIPLESS THE DOW CHEMICAL COMPANY (US) 1989-05-02 US claimed
JP-57151644-A None JP disclosed
WO-2024150594-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING SAME 帝人株式会社 2024-07-18 WO disclosed
EP-4397690-A1 POLYESTER-BASED PLASTICIZER, VINYL CHLORIDE-BASED RESIN COMPOSITION CONTAINING SAME, AND MOLDED ARTICLE THEREOF ADEKA CORPORATION (JP) 2024-07-10 EP disclosed
US-12024622-B2 Composition, thermoplastic resin composition using same, and molded article thereof ADEKA CORPORATION (JP) 2024-07-02 US disclosed
WO-2024122297-A1 FLAME-RETARDANT COMPOSITION, FLAME-RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE 株式会社ADEKA 2024-06-13 WO disclosed
US-11999838-B2 Resin additive composition, thermoplastic resin composition, and molded article thereof ADEKA CORPORATION (JP) 2024-06-04 US disclosed
US-5342869-A Monophosphonate, diphosphonate, phosphonate-phosphonite stabilizers against weathering SANDOZ LTD. (CH) 1994-08-30 US disclosed
EP-0595187-A1 A polycarbonate resin composition IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1994-05-04 EP disclosed
US-5077328-A Heat resistance in presence of filler ASAHI DENKA KOGYO K.K. (JP) 1991-12-31 US disclosed
EP-0335198-A2 Ignition resistant moulded article and method for preparing the same THE DOW CHEMICAL COMPANY (US) 1989-10-04 EP disclosed
US-4826900-A POLYTETRAFLUOROETHYLENE, DRIPLESS THE DOW CHEMICAL COMPANY (US) 1989-05-02 US disclosed
JP-S57151644-A STABILIZED COLORED POLYCARBONATE RESIN COMPOSITION TEIJIN CHEM LTD 1982-09-18 JP disclosed