Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PDE8B | O95263 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22815917 | 0.89 | CYP19A1 (0.42) | ALOX15L3MBTL1POLBMAPTMEN1 | |
| SCHEMBL22816961 | 0.89 | ALOX15 (0.42) | ALOX15L3MBTL1POLBMAPTCYP2C9 | |
| SCHEMBL22816229 | 0.82 | PTGDR2 (0.49) | ALOX15L3MBTL1POLBMAPTCYP2C9 | |
| SCHEMBL22816958 | 0.81 | TP53 (0.43) | ALOX15L3MBTL1MEN1KMT2AAKR1C3 | |
| SCHEMBL22816013 | 0.78 | AKR1C3 (0.47) | ALOX15L3MBTL1POLBMAPTMEN1 | |
| SCHEMBL22815942 | 0.78 | CYP19A1 (0.45) | ALOX15L3MBTL1POLBMAPTCCR2 | |
| SCHEMBL28950371 | 0.78 | ALOX15 (0.52) | ALOX15L3MBTL1POLBMAPTMEN1 | |
| SCHEMBL22815906 | 0.77 | ALOX15 (0.47) | ALOX15L3MBTL1POLBMAPTCYP2C9 | |
| SCHEMBL22816659 | 0.77 | ALOX15 (0.47) | ALOX15L3MBTL1POLBMAPTCCR2 | |
| SCHEMBL3746346 | 0.76 | CYP2C9 (0.44) | POLBMAPTCYP2C9PPARGCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |