Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484504 | 0.82 | RHEB (0.42) | RHEBCYP1A2CHEK2DGAT1 | |
| Trifluoroacetic Acid SCHEMBL22608146 | 0.79 | RHEB (0.40) | RHEBCYP1A2CHEK2DGAT1 | |
| SCHEMBL22608147 | 0.79 | RHEB (0.36) | RHEBCYP1A2CHEK2SCN10ACHRM5 | |
| SCHEMBL22815966 | 0.78 | L3MBTL1 (0.39) | RHEBDGAT1 | |
| SCHEMBL22807370 | 0.72 | RHEB (0.40) | RHEBCYP1A2SCN5ACHEK2SCN1A | |
| SCHEMBL22608306 | 0.69 | RHEB (0.47) | RHEBSCN5ACHEK2 | |
| SCHEMBL22807390 | 0.68 | RHEB (0.40) | RHEBSCN5ACHEK2SCN10A | |
| SCHEMBL22815960 | 0.66 | ALOX5AP (0.47) | CYP1A2SCN5AALOX5APFEN1SCN10A | |
| SCHEMBL22815962 | 0.66 | TP53 (0.47) | CYP1A2SCN5AALOX5APFEN1CYP3A4 | |
| SCHEMBL31374888 | 0.66 | CHRNA7 (0.47) | CYP1A2SCN5AALOX5APFEN1SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |