Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.41 |
| ▸ | PDE8B | O95263 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3731878 | 0.84 | UCHL1 (0.54) | UCHL1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL1412433 | 0.84 | UCHL1 (0.54) | UCHL1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL4221650 | 0.79 | UCHL1 (0.56) | UCHL1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL22817056 | 0.78 | CYP19A1 (0.44) | UCHL1MAPTALDH1A1KDM4EUSP2 | |
| SCHEMBL5517220 | 0.78 | UCHL1 (0.55) | UCHL1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL29067895 | 0.78 | AKR1C3 (0.57) | UCHL1MAPTAKR1C3PDE8BPTGER4 | |
| SCHEMBL1412486 | 0.77 | UCHL1 (0.52) | UCHL1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL7830775 | 0.76 | UCHL1 (0.53) | UCHL1MAPTAKR1C3PDE8BALDH1A1 | |
| SCHEMBL3730522 | 0.76 | UCHL1 (0.53) | UCHL1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL31728363 | 0.75 | UCHL1 (0.52) | UCHL1MAPTTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |