Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816274 | 0.82 | MAOB (0.59) | MAOBNPC1RAB9ASMN1; SMN2ABCB1 | |
| SCHEMBL22817113 | 0.81 | MAOB (0.49) | MAOBNPC1RAB9AAPPMRGPRX4 | |
| SCHEMBL23484500 | 0.80 | HDAC8 (0.47) | MAOBNPC1RAB9ASMN1; SMN2KDM5A | |
| SCHEMBL1028659 | 0.79 | HTR2A (0.47) | NPC1RAB9ASMN1; SMN2NFE2L2 | |
| SCHEMBL544520 | 0.79 | APP (0.61) | MAOBNPC1RAB9AABCB1APP | |
| SCHEMBL14777550 | 0.79 | NPC1 (0.51) | MAOBNPC1RAB9ASMN1; SMN2ABCB1 | |
| SCHEMBL190649 | 0.79 | MAOB (0.51) | MAOBNPC1RAB9AAPP | |
| SCHEMBL30313237 | 0.79 | APP (0.61) | MAOBNPC1RAB9AABCB1APP | |
| SCHEMBL15777881 | 0.78 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2KDM5AKDM4C | |
| SCHEMBL17050818 | 0.78 | MRGPRX4 (0.60) | MAOBNPC1RAB9ASMN1; SMN2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |