Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 5/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | AGXT | P21549 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331139 | 0.91 | MRGPRX4 (0.55) | MRGPRX4ENPP2APPABCB1ALDH1A1 | |
| SCHEMBL14985920 | 0.89 | ENPP2 (0.55) | MRGPRX4ENPP2APPALDH1A1NPC1 | |
| SCHEMBL29376917 | 0.88 | MRGPRX4 (0.60) | MRGPRX4ENPP2APPABCB1ALDH1A1 | |
| SCHEMBL8410512 | 0.88 | MRGPRX4 (0.60) | MRGPRX4ENPP2APPABCB1ALDH1A1 | |
| SCHEMBL1015213 | 0.87 | CCR5 (0.54) | MRGPRX4ENPP2APPALDH1A1MAOB | |
| SCHEMBL12954849 | 0.87 | ENPP2 (0.50) | MRGPRX4ENPP2APPABCB1ALDH1A1 | |
| SCHEMBL14854921 | 0.87 | NPC1 (0.51) | MRGPRX4ENPP2APPABCB1ALDH1A1 | |
| SCHEMBL3656490 | 0.85 | ENPP2 (0.51) | MRGPRX4ENPP2APPABCB1ALDH1A1 | |
| SCHEMBL29088121 | 0.84 | MRGPRX4 (0.59) | MRGPRX4 | |
| SCHEMBL8410186 | 0.84 | MRGPRX4 (0.55) | MRGPRX4ENPP2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | ACSS2, ACACB, ACAT2 | MRGPRX4 1931/4885ENPP2 501/4885APP 2384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.