Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.55 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816176 | 0.89 | S1PR1 (0.43) | S1PR1S1PR3KMO | |
| SCHEMBL22816289 | 0.85 | ALDH1A1 (0.50) | KMO | |
| SCHEMBL22816635 | 0.84 | S1PR1 (0.55) | S1PR1S1PR3KMOCSNK2A1 | |
| SCHEMBL1293435 | 0.78 | S1PR1 (0.55) | S1PR1S1PR3KMOCSNK2A1 | |
| SCHEMBL1293503 | 0.78 | S1PR1 (0.73) | S1PR1S1PR3 | |
| SCHEMBL22815574 | 0.78 | KDM4E (0.49) | — | |
| SCHEMBL22816285 | 0.76 | ALDH1A1 (0.50) | KMO | |
| SCHEMBL1293465 | 0.76 | S1PR1 (0.59) | S1PR1S1PR3KMO | |
| SCHEMBL1294117 | 0.75 | S1PR1 (0.58) | S1PR1S1PR3KMOCSNK2A1 | |
| SCHEMBL22816180 | 0.73 | S1PR1 (0.43) | S1PR1S1PR3KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |