Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816474 | 0.93 | MEN1 (0.46) | CYP19A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL22815669 | 0.91 | CYP19A1 (0.56) | CYP19A1AKR1C3MAPTMEN1KMT2A | |
| SCHEMBL21296878 | 0.90 | MEN1 (0.51) | CYP19A1AKR1C3MAPTMEN1KMT2A | |
| SCHEMBL22815684 | 0.89 | POLB (0.47) | CYP19A1AKR1C3MAPTMEN1KMT2A | |
| SCHEMBL22815716 | 0.89 | CYP19A1 (0.41) | CYP19A1AKR1C3MAPTMEN1KMT2A | |
| SCHEMBL22816699 | 0.89 | AKR1C3 (0.49) | AKR1C3MAPTMEN1KMT2AHPGD | |
| SCHEMBL22815534 | 0.86 | TP53 (0.47) | CYP19A1AKR1C3MAPTMEN1KMT2A | |
| SCHEMBL22815949 | 0.86 | AKR1C3 (0.47) | CYP19A1AKR1C3MAPTMEN1KMT2A | |
| SCHEMBL22816734 | 0.85 | CYP19A1 (0.48) | CYP19A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL22816823 | 0.84 | CYP19A1 (0.48) | CYP19A1AKR1C3MAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |