Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816473 | 0.92 | MEN1 (0.48) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL22816685 | 0.89 | CYP19A1 (0.46) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL21296940 | 0.89 | MEN1 (0.54) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL22815530 | 0.85 | TP53 (0.52) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL22815947 | 0.84 | AKR1C3 (0.45) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL22816737 | 0.84 | ALOX15 (0.49) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL22816828 | 0.83 | NPBWR1 (0.47) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL22816433 | 0.83 | EIF4E (0.48) | MEN1KMT2AMAPT | |
| SCHEMBL22816659 | 0.83 | ALOX15 (0.47) | AKR1C3MEN1KMT2AALOX15L3MBTL1 | |
| SCHEMBL22815714 | 0.81 | TP53 (0.54) | AKR1C3MEN1KMT2AALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |