Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | S100B | P04271 | 2/20 | 0.50 |
| ▸ | TERT | O14746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.50 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.50 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390975 | 1.00 | ADRB1 (0.66) | ADRB1HPGDMAPTMEN1KMT2A | |
| SCHEMBL3539353 | 0.98 | ADRB1 (0.68) | ADRB1HPGDMAPTMEN1KMT2A | |
| SCHEMBL24140572 | 0.93 | ADRB1 (0.68) | ADRB1HPGDMAPTMEN1KMT2A | |
| SCHEMBL14503598 | 0.88 | ADRB1 (0.53) | ADRB1HPGDMAPTMEN1KMT2A | |
| SCHEMBL30228205 | 0.83 | MEN1 (0.69) | ADRB1HPGDMAPTMEN1KMT2A | |
| SCHEMBL8864170 | 0.82 | GAA (0.65) | ADRB1HPGDMAPTMEN1KMT2A | |
| SCHEMBL5605736 | 0.82 | HPGD (0.54) | ADRB1HPGDMAPTMEN1KMT2A | |
| SCHEMBL9881498 | 0.82 | HPGD (0.50) | ADRB1HPGDMAPTMEN1KMT2A | |
| SCHEMBL1599707 | 0.82 | HPGD (0.50) | ADRB1HPGDMAPTMEN1KMT2A | |
| SCHEMBL6826402 | 0.82 | HPGD (0.50) | ADRB1HPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257180-A1 | AMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS, LLC (US) | 2020-12-24 | — | — | WO | disclosed |