SCHEMBL22820134

SCHEMBL22820134

CCCC1CCC(C2CCC(COc3ccc(B4OC(C)(C)C(C)(C)O4)cc3)CC2)CC1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LPL P06858 7/20 0.43
LIPG Q9Y5X9 7/20 0.43
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
AAK1 Q2M2I8 1/20 0.37
DGAT1 O75907 1/20 0.36
HIF1A Q16665 3/20 0.36
PARP15 Q460N3 1/20 0.35
PARP10 Q53GL7 1/20 0.35
PARP2 Q9UGN5 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26036118 0.96 LPL (0.46) LPLLIPGCA1CA2CA9
SCHEMBL21509219 0.88 CA1 (0.48) LPLLIPGCA1CA2CA9
SCHEMBL22815569 0.83 PARP15 (0.46) LPLLIPGCA1CA2CA9
SCHEMBL14480739 0.83 PARP15 (0.46) LPLLIPGCA1CA2CA9
SCHEMBL387330 0.82 PARP15 (0.47) LPLLIPGCA1CA2CA9
SCHEMBL19387935 0.81 LPL (0.46) LPLLIPGCA1CA2CA9
SCHEMBL17072248 0.81 MEN1 (0.47) LPLLIPGCA1CA2CA9
SCHEMBL16178844 0.80 CA1 (0.46) LPLLIPGCA1CA2CA9
SCHEMBL16622998 0.80 TDP1 (0.57) LPLLIPGCA1CA2CA9
SCHEMBL4664263 0.79 CXCR1 (0.46) CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-20200399539-A1 POLYMERIZABLE COMPOUND AS WELL AS LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE EACH INCLUDING POLYMERIZABLE COMPOUND DIC CORPORATION (JP) 2020-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 LPL 1920/4885LIPG 3805/4885CA1 1223/4885
US-20200399539-A1 POLYMERIZABLE COMPOUND AS WELL AS LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE EACH INCLUDING POLYMERIZABLE COMPOUND OCIAD2, PKN2, SKP1 LPL 1920/4885LIPG 3805/4885CA1 1223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.