Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22819946 | 0.89 | HPGD (0.68) | HTTHSD17B10HPGDKDM4ELMNA | |
| SCHEMBL22820172 | 0.87 | HPGD (0.64) | HTTHSD17B10HPGDKDM4ELMNA | |
| SCHEMBL22820091 | 0.86 | HTT (0.65) | HTTHSD17B10HPGDKDM4ELMNA | |
| SCHEMBL23781713 | 0.86 | HPGD (0.65) | HPGDLMNAALDH1A1MAPTCYP1A2 | |
| SCHEMBL22819914 | 0.85 | MEN1 (0.57) | HTTHSD17B10HPGDKDM4ELMNA | |
| SCHEMBL22819978 | 0.85 | LMNA (0.57) | HTTHSD17B10HPGDKDM4ELMNA | |
| SCHEMBL22819972 | 0.83 | KDM4E (0.60) | HTTHSD17B10HPGDKDM4ELMNA | |
| SCHEMBL22819945 | 0.83 | NPC1 (0.55) | HTTHSD17B10HPGDKDM4ELMNA | |
| SCHEMBL22819924 | 0.83 | HTT (0.54) | HTTHSD17B10HPGDKDM4ELMNA | |
| SCHEMBL22820217 | 0.82 | LMNA (0.56) | HTTHSD17B10HPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020255425-A1 | ANTI-HBV AGENT | 国立研究開発法人理化学研究所 | 2020-12-24 | — | — | WO | disclosed |