Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22819978 | 0.84 | LMNA (0.57) | LMNACYP2C19NPC1RAB9AKDM4E | |
| SCHEMBL22820178 | 0.83 | LMNA (0.69) | LMNANPC1RAB9AKDM4EMAPT | |
| SCHEMBL22819984 | 0.82 | KDM4E (0.65) | LMNANPC1RAB9AKDM4EMAPT | |
| SCHEMBL22819979 | 0.82 | LMNA (0.59) | LMNACYP2C19NPC1RAB9AKDM4E | |
| SCHEMBL28436829 | 0.82 | CYP1A2 (0.69) | LMNACYP2C19RAB9AKDM4EMAPT | |
| SCHEMBL22819980 | 0.82 | KMT2A (0.62) | LMNANPC1RAB9AKDM4EMAPT | |
| SCHEMBL22820062 | 0.82 | HTT (0.67) | LMNACYP2C19NPC1RAB9AKDM4E | |
| SCHEMBL22819939 | 0.81 | LMNA (0.70) | LMNANPC1RAB9AKDM4EMAPT | |
| SCHEMBL22819976 | 0.81 | LMNA (0.57) | LMNANPC1RAB9AKDM4EMAPT | |
| SCHEMBL22819974 | 0.81 | CYP1A2 (0.60) | LMNACYP2C19NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020255425-A1 | ANTI-HBV AGENT | 国立研究開発法人理化学研究所 | 2020-12-24 | — | — | WO | disclosed |