Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.59 |
| ▸ | METAP2 | P50579 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22819980 | 0.93 | KMT2A (0.62) | KMT2AMEN1KDM4ERAB9AKCNK3 | |
| SCHEMBL5226578 | 0.89 | KCNK3 (0.66) | KMT2AMEN1KDM4ERAB9AKCNK3 | |
| SCHEMBL22819921 | 0.84 | RXFP1 (0.61) | KCNK3KCNK9RXFP1 | |
| SCHEMBL22820172 | 0.82 | HPGD (0.64) | KMT2AMEN1KDM4ERAB9AKCNK3 | |
| SCHEMBL22820076 | 0.82 | RAB9A (0.67) | KMT2AMEN1KDM4ERAB9AKCNK9 | |
| SCHEMBL22820075 | 0.81 | HTT (0.61) | KMT2AMEN1KDM4ERAB9AHSD17B10 | |
| SCHEMBL22820037 | 0.81 | HPGD (0.54) | KMT2AMEN1KDM4ERAB9AKCNK3 | |
| SCHEMBL12368122 | 0.81 | KMT2A (0.79) | KMT2AMEN1KDM4ERAB9AKCNK3 | |
| SCHEMBL2362772 | 0.81 | KMT2A (0.82) | KMT2AMEN1KDM4ERAB9AKCNK3 | |
| SCHEMBL6802094 | 0.80 | KMT2A (1.00) | KMT2AMEN1KDM4ERAB9AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020255425-A1 | ANTI-HBV AGENT | 国立研究開発法人理化学研究所 | 2020-12-24 | — | — | WO | disclosed |