Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19356146 | 0.77 | — | — | |
| SCHEMBL10643014 | 0.74 | CES2 (0.32) | — | |
| SCHEMBL10643011 | 0.74 | CES2 (0.32) | — | |
| SCHEMBL18737291 | 0.72 | — | — | |
| SCHEMBL13370623 | 0.72 | — | — | |
| SCHEMBL23265970 | 0.69 | TSHR (0.33) | ALDH1A1TSHR | |
| SCHEMBL19424071 | 0.69 | — | — | |
| SCHEMBL8931299 | 0.67 | — | — | |
| SCHEMBL19177004 | 0.67 | — | — | |
| SCHEMBL25973370 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257549-A2 | COMPOUNDS FOR TREATMENT OF PD-L1 DISEASES | CHEMOCENTRYX, INC. (US) | 2020-12-24 | — | — | WO | disclosed |