SCHEMBL2282162

SCHEMBL2282162

CN(CC(=O)O)C(=O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
HDAC1 Q13547 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
DPP4 P27487 1/20 0.48
PREP P48147 1/20 0.48
FAP Q12884 1/20 0.48
PIN1 Q13526 1/20 0.48
EGFR P00533 2/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
HSD11B1 P28845 1/20 0.47
F2 P00734 1/20 0.46
CDK4 P11802 1/20 0.45
CCND1 P24385 1/20 0.45
MLYCD O95822 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1372985 0.98 KMT2A (0.51) KMT2AMEN1HDAC1HDAC6DPP4
SCHEMBL30530699 0.93 HPGD (0.59) KMT2AMEN1HDAC1HDAC6DPP4
SCHEMBL11107022 0.91 HDAC1 (0.45) KMT2AMEN1HDAC1HDAC6PIN1
SCHEMBL1221812 0.89 MAPT (0.59) PIN1ALDH1A1HPGDCDK4CCND1
SCHEMBL8729148 0.88 NR4A2 (0.65) KMT2AMEN1HDAC1HDAC6DPP4
SCHEMBL11606625 0.86 ALDH1A1 (0.55) KMT2AMEN1HDAC1HDAC6DPP4
SCHEMBL13337842 0.86 KMT2A (0.51) KMT2AMEN1HDAC1HDAC6DPP4
SCHEMBL3362719 0.85 KMT2A (0.55) KMT2AMEN1HDAC1HDAC6DPP4
SCHEMBL4588789 0.84 KMT2A (0.54) KMT2AMEN1HDAC1HDAC6DPP4
SCHEMBL12302105 0.84 KMT2A (0.48) KMT2AMEN1ALDH1A1CDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103739827-B Resin combination 味之素株式会社 2016-11-23 CN claimed
EP-2698393-B1 Resin composition AJINOMOTO KK (JP) 2015-08-19 EP claimed
CN-103739827-A Resin composition AJINOMOTO KK 2014-04-23 CN claimed
EP-2698393-A1 Resin composition Ajinomoto Co., Inc. (JP) 2014-02-19 EP claimed
US-20130165446-A1 BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE HORIKOSHI, HIROYOSHI (CA) 2013-06-27 US claimed
EP-2581373-A1 BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE Fujita, Takashi (JP) 2013-04-17 EP claimed
EP-2174969-A1 RESIN COMPOSITION Ajinomoto Co., Inc. (JP) 2010-04-14 EP claimed
CN-101687979-A Resin composition AJINOMOTO KK 2010-03-31 CN claimed
US-20090030158-A1 RESIN COMPOSITION AJINOMOTO CO., INC (JP) 2009-01-29 US claimed
CN-113444340-B Resin composition 味之素株式会社 2025-06-10 CN disclosed
CN-120009437-A Method for simultaneously measuring multiple volatile organic compounds metabolites in urine 中国疾病预防控制中心环境与健康相关产品安全所 2025-05-16 CN disclosed
WO-2025100510-A1 ADHESIVE SHEET AND HEAT DISSIPATION MEMBER 新光電気工業株式会社 2025-05-15 WO disclosed
CN-118544649-A Metal foil laminate for use in collector layer and method for producing same 味之素株式会社 2024-08-27 CN disclosed
CN-118438680-A Method for adhering adherend 味之素株式会社 2024-08-06 CN disclosed
EP-0574028-A1 Dipeptide analogs of aspertame and process to prepare them as well as a new preparation of aspertame HAMPSHIRE CHEMICAL CORP. (US) 1993-12-15 EP disclosed
US-4873359-A Process for preparing as partyl-phenylalanine dipeptides W. R. GRACE & CO. - CONN. (US) 1989-10-10 US disclosed
US-4810817-A ARTIFICIAL SWEETENERS W. R. GRACE & CO. (US) 1989-03-07 US disclosed
US-4710583-A ENZYMATIC COUPLING OF PHENYLSERINE WITH ASPARTIC ACID; HYDROGENATION W. R. GRACE & CO. (US) 1987-12-01 US disclosed
EP-0220923-A2 Dipeptides and process W.R. Grace & Co.-Conn. (US) 1987-05-06 EP disclosed
US-4494547-A 2H-isoindolediones, their synthesis and use as radiosensitizers NORTH CAROLINA CENTRAL UNIVERSITY (US) 1985-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030158-A1 RESIN COMPOSITION PPA1, PTGER1, TAF5 KMT2A 2433/4885MEN1 3932/4885HDAC1 1492/4885
US-20130165446-A1 BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE PPARG, PPARA, PPARD KMT2A 1996/4885MEN1 4822/4885HDAC1 126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.