Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.76 |
| ▸ | INSR | P06213 | 1/20 | 0.64 |
| ▸ | IGF1R | P08069 | 1/20 | 0.64 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22595126 | 0.92 | EGFR (0.77) | EGFR | |
| SCHEMBL22821823 | 0.91 | EGFR (0.72) | EGFRINSRIGF1RALK | |
| SCHEMBL22822013 | 0.91 | EGFR (0.77) | EGFR | |
| SCHEMBL22821817 | 0.90 | EGFR (0.77) | EGFRINSRIGF1RALK | |
| SCHEMBL24178906 | 0.90 | EGFR (0.79) | EGFRINSRIGF1RALK | |
| SCHEMBL22822088 | 0.89 | EGFR (0.72) | EGFRINSRIGF1RALK | |
| SCHEMBL22804399 | 0.89 | EGFR (0.63) | EGFRINSRIGF1RALK | |
| SCHEMBL22822099 | 0.88 | EGFR (0.74) | EGFRINSRIGF1RALK | |
| SCHEMBL26630881 | 0.87 | EGFR (0.60) | EGFRINSRIGF1RALK | |
| SCHEMBL29710725 | 0.87 | EGFR (0.58) | EGFRINSRIGF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020253862-A1 | NITROGEN-CONTAINING ARYL PHOSPHORUS OXIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-24 | — | — | WO | disclosed |