Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.63 |
| ▸ | INSR | P06213 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22804364 | 0.91 | EGFR (0.60) | EGFRINSRIGF1RALK | |
| SCHEMBL22822010 | 0.89 | EGFR (0.76) | EGFRINSRIGF1RALK | |
| SCHEMBL24178909 | 0.89 | EGFR (0.65) | EGFRINSRIGF1RALK | |
| SCHEMBL22804402 | 0.88 | EGFR (0.63) | EGFRINSRIGF1RALK | |
| SCHEMBL24605929 | 0.87 | INSR (0.50) | EGFRINSRIGF1RALK | |
| SCHEMBL24606019 | 0.87 | EGFR (0.51) | EGFRINSRIGF1RALK | |
| SCHEMBL22025925 | 0.86 | EGFR (0.79) | EGFR | |
| SCHEMBL24954018 | 0.85 | EGFR (0.64) | EGFRINSRIGF1RALK | |
| SCHEMBL23759671 | 0.85 | EGFR (0.71) | EGFRINSRIGF1RALK | |
| SCHEMBL29084167 | 0.84 | EGFR (0.70) | EGFRINSRIGF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020253862-A1 | NITROGEN-CONTAINING ARYL PHOSPHORUS OXIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-24 | — | — | WO | disclosed |