Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1333474 | 0.88 | TSHR (0.39) | SLC6A9SLC6A5TSHRHTR2AHTR2C | |
| SCHEMBL1331691 | 0.86 | TSHR (0.52) | SLC6A9SLC6A5TSHRHTR2AHTR2C | |
| SCHEMBL1333649 | 0.86 | TSHR (0.52) | SLC6A9SLC6A5TSHRHTR2AHTR2C | |
| SCHEMBL1331693 | 0.86 | TSHR (0.52) | SLC6A9SLC6A5TSHRHTR2AHTR2C | |
| SCHEMBL2281930 | 0.82 | PTGDR2 (0.40) | SLC6A9SLC6A5TSHRHTR2AHTR2C | |
| SCHEMBL1333478 | 0.77 | PTGDR2 (0.45) | PTGDR2AVPR2GPR27 | |
| SCHEMBL1333476 | 0.77 | PTGDR2 (0.48) | PTGDR2HTT | |
| SCHEMBL1331640 | 0.73 | PTGDR2 (0.60) | TSHRPTGDR2 | |
| SCHEMBL1333433 | 0.73 | TSHR (0.50) | SLC6A9SLC6A5TSHRHTR2AHTR2C | |
| SCHEMBL2103120 | 0.72 | TSHR (0.47) | TSHRHTR2AHTR2CHTR2BPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003703-B2 | Phenoxiacetic acid derivatives | ASTRAZENECA AB (SE) | 2011-08-23 | — | — | US | disclosed |
| US-20060293352-A1 | Phenoxiacetic acid derivatives | ASTRAZENECA AB (SE) | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293352-A1 | Phenoxiacetic acid derivatives | HRH2, HRH1, HCAR2 | SLC6A9 3066/4885SLC6A5 2366/4885TSHR 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.