Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | MITF | O75030 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | TYMS | P04818 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | DDIT3 | P35638 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24292224 | 0.88 | JAK2 (0.68) | JAK2MEN1KMT2APAX8MAPT | |
| SCHEMBL6428842 | 0.85 | KMT2A (0.64) | JAK2MEN1KMT2AMAPTLMNA | |
| SCHEMBL6429046 | 0.82 | JAK2 (0.74) | JAK2MEN1KMT2APAX8MAPT | |
| SCHEMBL22804220 | 0.81 | JAK2 (0.73) | JAK2MEN1KMT2APAX8MAPT | |
| SCHEMBL22822561 | 0.81 | JAK2 (0.77) | JAK2MEN1KMT2APAX8MAPT | |
| SCHEMBL6428416 | 0.81 | JAK2 (0.73) | JAK2MEN1KMT2APAX8MAPT | |
| SCHEMBL6427451 | 0.81 | JAK2 (0.73) | JAK2MEN1KMT2APAX8MAPT | |
| SCHEMBL6428809 | 0.81 | JAK2 (0.73) | JAK2MEN1KMT2APAX8MAPT | |
| SCHEMBL13219526 | 0.81 | JAK2 (1.00) | JAK2MEN1KMT2APAX8MAPT | |
| SCHEMBL1520209 | 0.80 | DDIT3 (0.78) | JAK2MEN1KMT2APAX8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12428389-B2 | Diarylamide compound and application thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2025-09-30 | — | — | US | claimed |
| US-20230045031-A1 | Diarylamide Compound and Application Thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2023-02-09 | — | — | US | claimed |
| EP-3984534-A1 | DIARYLAMIDE COMPOUND AND APPLICATION THEREOF | Peking University (CN) | 2022-04-20 | — | — | EP | claimed |
| CN-112107568-B | Diaryl amide compound and application thereof | 北京龙嘉博创医药科技有限公司 | 2022-03-25 | — | — | CN | claimed |
| WO-2020253802-A1 | DIARYLAMIDE COMPOUND AND APPLICATION THEREOF | 北京大学 | 2020-12-24 | — | — | WO | claimed |
| CN-112107568-A | Diaryl amide compound and application thereof | 北京大学 | 2020-12-22 | — | — | CN | claimed |
| US-12428389-B2 | Diarylamide compound and application thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2025-09-30 | — | — | US | disclosed |
| US-20230045031-A1 | Diarylamide Compound and Application Thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2023-02-09 | — | — | US | disclosed |
| US-20230045031-A1 | Diarylamide Compound and Application Thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2023-02-09 | — | — | US | disclosed |
| EP-3984534-A1 | DIARYLAMIDE COMPOUND AND APPLICATION THEREOF | Peking University (CN) | 2022-04-20 | — | — | EP | disclosed |
| EP-3984534-A1 | DIARYLAMIDE COMPOUND AND APPLICATION THEREOF | Peking University (CN) | 2022-04-20 | — | — | EP | disclosed |
| CN-112107568-B | Diaryl amide compound and application thereof | 北京龙嘉博创医药科技有限公司 | 2022-03-25 | — | — | CN | disclosed |
| WO-2020253802-A1 | DIARYLAMIDE COMPOUND AND APPLICATION THEREOF | 北京大学 | 2020-12-24 | — | — | WO | disclosed |
| WO-2020253802-A1 | DIARYLAMIDE COMPOUND AND APPLICATION THEREOF | 北京大学 | 2020-12-24 | — | — | WO | disclosed |
| CN-112107568-A | Diaryl amide compound and application thereof | 北京大学 | 2020-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12428389-B2 | Diarylamide compound and application thereof | SLC14A1, SLC28A1, SLC28A2 | JAK2 3981/4885MEN1 3485/4885KMT2A 3036/4885 |
| US-20230045031-A1 | Diarylamide Compound and Application Thereof | SLC14A1, SLC28A1, SLC28A2 | JAK2 3981/4885MEN1 3485/4885KMT2A 3036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.