SLC14A1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL15285336	1.00	1/20
SCHEMBL19769162	0.81	1/20
SCHEMBL8027975	0.80	1/20
SCHEMBL15287661	0.80	1/20
SCHEMBL15287921	0.80	1/20
SCHEMBL15287958	0.80	1/20
SCHEMBL15285224	0.79	1/20
SCHEMBL15287920	0.79	1/20
SCHEMBL15287899	0.78	1/20
SCHEMBL15285589	0.77	1/20
SCHEMBL15287694	0.77	1/20
SCHEMBL15285338	0.77	1/20
SCHEMBL15285303	0.76	1/20
SCHEMBL15285660	0.76	1/20
SCHEMBL15287947	0.76	1/20
SCHEMBL15285274	0.74	1/20
SCHEMBL12562465	0.71	1/20
SCHEMBL15287960	0.71	1/20
SCHEMBL15285262	0.71	1/20
SCHEMBL15287910	0.71	1/20

Clinical trials — most relevant to SLC14A1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effect of Age on the Renal Clearance of Adefovir	PHASE4	WITHDRAWN
Febuxostat, Blood Pressure and the Intrarenal Renin-Angiotensin System (RAS)	PHASE4	COMPLETED
L-arginine Treatment in Mild Hypertension	PHASE4	UNKNOWN
Prevention of Renal Complications of Diabetes With Thiamine	PHASE4	UNKNOWN
Hepato-renal Regulation of Water Conservation in Heart Failure Patients With SGLT-2 Inhibitor Treatment	PHASE4	COMPLETED
A Phase I/II Open-label Safety and Efficacy Study of LNP.UCD.ABE in Patients With Urea Cycle Disorders.	PHASE1/PHASE2	NOT_YET_RECRUITING
Effect of, OAT3, on the Renal Secretion of Cefotaxime	PHASE1	COMPLETED
Safety and Pharmacokinetic Profiles of Two Formulations of CO-1.01 in Patients With Advanced Solid Tumors	PHASE1	COMPLETED
Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters	EARLY_PHASE1	COMPLETED
Multi-omics Study in Citrin Deficiency	nan	ACTIVE_NOT_RECRUITING
Fecal Microbiota Transplantation as a Therapeutic Strategy in the Progression of Chronic Kidney Disease	nan	COMPLETED
Longitudinal Study of Urea Cycle Disorders	nan	RECRUITING
Bile Acid Effects in Fetal Arrhythmia Study	nan	UNKNOWN
Oxalate and Citrate in Humans - Response to Citrate	nan	RECRUITING
Genetics of Hyperuricemia Therapy in Hmong	nan	COMPLETED
Impact of Genetics on Metformin Pharmacokinetics	nan	COMPLETED
Alpha -1- Microglobulin (α1M) as an Early Biomarker in Renal Extrahepatic Manifestations of HCV-infection	nan	UNKNOWN
Epidemiology of Gout in French Polynesia	nan	COMPLETED
Effect of an Polyphenolic Beverage in Healthy Volunteers	nan	ACTIVE_NOT_RECRUITING
Biological Determinants of Peritoneal Dialysis	nan	COMPLETED
When the Kidney Reacts to Nutritional Changes	nan	COMPLETED
Renal Transporters After Renal Transplantation	nan	UNKNOWN
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy	nan	COMPLETED
Supplementation With Altha-aminoacids and Systemiec Inflammatory Response in Long-distance Runners.	nan	UNKNOWN
Urinary Kallikrein and Hypertension: A Prospective Study	nan	COMPLETED
ADPKD Alterations in Hepatic Transporter Function	nan	COMPLETED
Incidence of Iron Deficiency in Polycythemia Vera (PV) and Association With Disease Features	nan	UNKNOWN
Oxalate and Citrate	nan	RECRUITING
Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD	nan	COMPLETED
Prevalence and Risk Factors of Nephrocalcinosis in Children at Sohag University Hospital	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a SLC14A1 binder may also engage these)

Protein	Name	Similarity
Q8VHL0	—	1.000	Q8VHL0 →
C5MK33	—	0.999	C5MK33 →
Q5QF96	—	0.999	Q5QF96 →
P97689	—	0.998	P97689 →
D3INW7	—	0.997	D3INW7 →
Q28614	—	0.992	Q28614 →
Q8R4T9	—	0.980	Q8R4T9 →
Q62668	—	0.978	Q62668 →
Q62773	—	0.978	Q62773 →
O88575	—	0.978	O88575 →
Q62674	—	0.977	Q62674 →
E9PXX9	—	0.977	E9PXX9 →
ERMP1	Endoplasmic reticulum metallopeptidase 1	0.976	landscape →
Q0DWA9	—	0.976	Q0DWA9 →
SLC28A1	Sodium/nucleoside cotransporter 1	0.976	landscape →
Q0WMJ8	—	0.976	Q0WMJ8 →
Q5Z413	—	0.976	Q5Z413 →
Q15849	—	0.976	Q15849 →
Q5RCE2	—	0.976	Q5RCE2 →
STT3A	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A	0.976	landscape →
A9UY97	—	0.975	A9UY97 →
C4LD54	—	0.975	C4LD54 →
SLC28A2	Sodium/nucleoside cotransporter 2	0.975	landscape →
Q8VIH3	—	0.975	Q8VIH3 →
Q641M3	—	0.975	Q641M3 →
Q8K596	—	0.975	Q8K596 →
O18875	—	0.975	O18875 →
Q7EYH7	—	0.975	Q7EYH7 →
Q8W469	—	0.975	Q8W469 →
Q9Y487	—	0.975	Q9Y487 →