SCHEMBL2282279

SCHEMBL2282279

O=C(O)COC(CC(=O)O)(CC(=O)O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
TSHR P16473 2/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
CTH P32929 1/20 0.36
CBS P35520 1/20 0.36
THPO P40225 1/20 0.36
THRB P10828 1/20 0.35
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
ACLY P53396 3/20 0.33
CPT2 P23786 2/20 0.32
KDM4E B2RXH2 1/20 0.30
FFAR1 O14842 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8371321 0.98 ALDH1A1 (0.39) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL28772080 0.98 ALDH1A1 (0.39) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL6754637 0.89 ALDH1A1 (0.36) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL6602222 0.84 CYP2D6 (0.39) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL27838760 0.79 ALDH1A1 (0.32) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL13523682 0.78 ALDH1A1 (0.39) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL28427067 0.78 FFAR3 (0.35) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL11855111 0.78 ALDH1A1 (0.39) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL4329618 0.78 CYP2D6 (0.42) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
SCHEMBL28166028 0.78 ALDH1A1 (0.31) ALDH1A1TSHRCYP2D6CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4219672-A Ether carboxylic acids HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1980-08-26 US claimed
EP-2354196-A1 Water-based ink for ink jet recording Brother Kogyo Kabushiki Kaisha (JP) 2011-08-10 EP disclosed
US-20110187799-A1 Water-Based Ink for Ink Jet Recording BROTHER KOGYO KABUSHIKI KAISHA (JP) 2011-08-04 US disclosed
US-4219672-A Ether carboxylic acids HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1980-08-26 US disclosed
US-4153726-A Skin protection agents containing polyethercarboxylic acids HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1979-05-08 US disclosed