SCHEMBL22823769

SCHEMBL22823769

CC1(C)c2ccccc2-c2c(Nc3ccc4c(c3)C3(c5ccccc5-c5ccccc53)c3ccccc3-4)cccc21

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 4/20 0.37
PGR P06401 2/20 0.33
MAPK14 Q16539 8/20 0.33
MAPK13 O15264 1/20 0.33
MAPK12 P53778 1/20 0.33
MAPK11 Q15759 1/20 0.33
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
MET P08581 1/20 0.31
GNG2 P59768 2/20 0.30
GNB1 P62873 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15892496 0.95 PDK2 (0.37) PDK2PGRMAPK14MAPK13MAPK12
SCHEMBL29373580 0.95 PDK2 (0.37) PDK2PGRMAPK14MAPK13MAPK12
SCHEMBL16383580 0.93 PDK2 (0.40) PDK2PGRMAPK14MAPK13MAPK12
SCHEMBL29899148 0.93 PDK2 (0.40) PDK2PGRMAPK14MAPK13MAPK12
SCHEMBL29440303 0.93 PDK2 (0.40) PDK2PGRMAPK14MAPK13MAPK12
SCHEMBL23288331 0.92 PDK2 (0.37) PDK2PGRMAPK14MAPK13MAPK12
SCHEMBL24078499 0.90 PDK2 (0.38) PDK2PGRMAPK14MAPK13MAPK12
SCHEMBL25657123 0.90 PDK2 (0.38) PDK2PGRMAPK14MAPK13MAPK12
SCHEMBL20434441 0.90 PDK2 (0.41) PDK2PGRMAPK14MAPK13MAPK12
SCHEMBL21975933 0.89 PDK2 (0.35) PDK2PGRMAPK14MAPK13MAPK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11770973-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-26 US disclosed
US-11770973-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-26 US disclosed
US-20220127251-A1 PROCESS FOR THE PRODUCTION OF ARYLAMINES MERCK PATENT GMBH (DE) 2022-04-28 US disclosed
WO-2021080280-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2021-04-29 WO disclosed
US-20200403164-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127251-A1 PROCESS FOR THE PRODUCTION OF ARYLAMINES MAOB, TYR, INMT PDK2 805/4885PGR 3313/4885MAPK14 1988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.