Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22825391 | 0.97 | SCN9A (0.33) | SPHK2STIM1ORAI1SCN9AALOX5 | |
| SCHEMBL21786426 | 0.89 | PPARD (0.33) | THRATHRBSTIM1ORAI1S1PR1 | |
| SCHEMBL21786487 | 0.86 | USP7 (0.36) | SCN9A | |
| SCHEMBL22791224 | 0.85 | PPARD (0.34) | STIM1ORAI1SCN9A | |
| SCHEMBL22825614 | 0.84 | STIM1 (0.35) | STIM1ORAI1SCN9APTGS1PTGS2 | |
| SCHEMBL21786433 | 0.82 | SCN9A (0.37) | SCN9A | |
| SCHEMBL24127463 | 0.81 | AGER (0.32) | SPHK2 | |
| SCHEMBL21786504 | 0.80 | PTGDR2 (0.36) | STIM1ORAI1SCN9AALOX5PTGS1 | |
| SCHEMBL21786492 | 0.77 | DYRK3 (0.32) | STIM1ORAI1ALOX5PTGS1PTGS2 | |
| SCHEMBL22790953 | 0.75 | PPARD (0.34) | STIM1ORAI1SCN9APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257261-A1 | SUBSTITUTED HETEROCYCLES AS c-MYC TARGETING AGENTS | NORTHWESTERN UNIVERSITY (US) | 2020-12-24 | — | — | WO | disclosed |