Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22959029 | 0.78 | KCNH2 (0.55) | KCNH2TLR7TLR8 | |
| SCHEMBL22958983 | 0.74 | KCNH2 (0.56) | KCNH2TLR7TLR8 | |
| SCHEMBL22958987 | 0.71 | GAA (0.36) | ALDH1A1KCNH2HSP90AB1KDM4ETDP1 | |
| SCHEMBL18558889 | 0.69 | CYP3A4 (0.55) | CA2ALDH1A1CYP3A4TDP1LMNA | |
| SCHEMBL29601605 | 0.67 | KCNH2 (0.39) | ALDH1A1KCNH2KDM4EELANETLR7 | |
| SCHEMBL22819395 | 0.67 | KCNH2 (0.39) | ALDH1A1KCNH2KDM4EELANETLR7 | |
| SCHEMBL22825595 | 0.66 | KCNH2 (0.55) | ALDH1A1KCNH2TLR7TLR8 | |
| SCHEMBL18856236 | 0.66 | CYP3A4 (0.51) | CA2ALDH1A1CYP3A4TDP1LMNA | |
| SCHEMBL22844439 | 0.65 | TSHR (0.50) | CA2ALDH1A1CYP3A4TDP1LMNA | |
| SCHEMBL21325598 | 0.64 | TLR8 (0.69) | KCNH2TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020255039-A1 | COMBINATION OF HEPATITIS B VIRUS (HBV) VACCINES AND QUINAZOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-12-24 | — | — | WO | disclosed |