SCHEMBL22832434

SCHEMBL22832434

CCCOCCOCCOCCOC(=O)c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.79
▸ TDP1 Q9NUW8 4/20 0.61
▸ ALDH1A1 P00352 5/20 0.56
▸ ESR1 P03372 3/20 0.56
▸ TSHR P16473 3/20 0.56
▸ SLC6A2 P23975 2/20 0.56
▸ CHRM1 P11229 1/20 0.56
▸ KDR P35968 1/20 0.56
▸ KMT2A Q03164 2/20 0.51
▸ MAPT P10636 2/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ THRB P10828 1/20 0.51
▸ HPGD P15428 1/20 0.51
▸ MAPK1 P28482 3/20 0.50
▸ SCN5A Q14524 2/20 0.50
▸ SLC6A3 Q01959 2/20 0.50
▸ HIF1A Q16665 1/20 0.50
▸ ABCB11 O95342 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ ADRA2B P18089 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1919741 1.00 LMNA (0.79) LMNATDP1ALDH1A1ESR1TSHR
SCHEMBL22832552 1.00 LMNA (0.79) LMNATDP1ALDH1A1ESR1TSHR
Propanol SCHEMBL7990856 0.91 LMNA (0.71) LMNATDP1ALDH1A1ESR1TSHR
SCHEMBL15512201 0.91 TDP1 (0.73) LMNATDP1ALDH1A1ESR1TSHR
SCHEMBL15512375 0.91 TDP1 (0.73) LMNATDP1ALDH1A1ESR1TSHR
SCHEMBL15512622 0.91 TDP1 (0.73) LMNATDP1ALDH1A1ESR1TSHR
SCHEMBL3870579 0.91 TDP1 (0.73) LMNATDP1ALDH1A1ESR1TSHR
SCHEMBL1555414 0.91 TDP1 (0.73) LMNATDP1ALDH1A1ESR1TSHR
SCHEMBL15512301 0.91 TDP1 (0.73) LMNATDP1ALDH1A1ESR1TSHR
SCHEMBL205788 0.91 TDP1 (0.73) LMNATDP1ALDH1A1ESR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12365785-B2 Glycol ether aryl ester plasticizer EASTMAN CHEMICAL COMPANY (US) 2025-07-22 — — US claimed
US-20220227962-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER EASTMAN CHEMICAL COMPANY (US) 2022-07-21 — — US claimed
EP-3990532-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER Eastman Chemical Company (US) 2022-05-04 — — EP claimed
WO-2020263593-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER EASTMAN CHEMICAL COMPANY (US) 2020-12-30 — — WO claimed
US-12365785-B2 Glycol ether aryl ester plasticizer EASTMAN CHEMICAL COMPANY (US) 2025-07-22 — — US disclosed
US-20220227962-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER EASTMAN CHEMICAL COMPANY (US) 2022-07-21 — — US disclosed
EP-3990532-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER Eastman Chemical Company (US) 2022-05-04 — — EP disclosed
WO-2020263593-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER EASTMAN CHEMICAL COMPANY (US) 2020-12-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12365785-B2 Glycol ether aryl ester plasticizer DAGLA, DDT, PPARG LMNA 1384/4885TDP1 1253/4885ALDH1A1 2955/4885
US-20220227962-A1 GLYCOL ETHER ARYL ESTER PLASTICIZER DAGLA, DDT, PPARG LMNA 1384/4885TDP1 1253/4885ALDH1A1 2955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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