Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 15/20 | 0.53 |
| ▸ | FLT3 | P36888 | 9/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.51 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | CDK9 | P50750 | 4/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.43 |
| ▸ | CDK7 | P50613 | 3/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.43 |
| ▸ | CCNH | P51946 | 2/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279007 | 0.87 | MKNK2 (0.49) | MKNK2FLT3MKNK1CDK2CDK9 | |
| SCHEMBL2286766 | 0.85 | CDK2 (0.55) | MKNK2FLT3CDK2CDK9CDK1 | |
| SCHEMBL2283663 | 0.84 | CDK2 (0.61) | MKNK2FLT3CDK2CDK9CDK1 | |
| SCHEMBL2286235 | 0.84 | MKNK2 (0.47) | MKNK2FLT3MKNK1CDK2CDK9 | |
| SCHEMBL2287258 | 0.84 | MKNK2 (0.55) | MKNK2FLT3MKNK1CDK2CDK9 | |
| SCHEMBL2287133 | 0.84 | MKNK2 (0.51) | MKNK2FLT3MKNK1CDK2CDK9 | |
| SCHEMBL2281907 | 0.83 | MKNK2 (0.52) | MKNK2FLT3MKNK1MAPT | |
| SCHEMBL2283318 | 0.83 | MKNK2 (0.52) | MKNK2FLT3MKNK1CDK2CDK9 | |
| SCHEMBL2289294 | 0.81 | CDK2 (0.54) | FLT3CDK2CDK9CDK1CDK7 | |
| SCHEMBL2282010 | 0.81 | MKNK2 (0.49) | MKNK2FLT3MKNK1CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | MKNK2 4101/4885FLT3 216/4885MKNK1 4404/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | MKNK2 4185/4885FLT3 211/4885MKNK1 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.