Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8819539 | 0.78 | TSHR (0.58) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL13140569 | 0.75 | KMT2A (0.48) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL4267841 | 0.75 | KMT2A (0.48) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL10814681 | 0.74 | KMT2A (0.50) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL10813189 | 0.73 | MEN1 (0.46) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL22833022 | 0.73 | MAPT (0.43) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL13545621 | 0.72 | GAA (0.69) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL2219482 | 0.72 | ALDH1A1 (0.58) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL5416914 | 0.72 | HIF1A (0.52) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL4279649 | 0.72 | MEN1 (0.48) | KMT2AMEN1MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020260857-A1 | HYDROXAMATE COMPOUNDS AS ANTAGONISTS OF THE ADENOSINE A2A RECEPTOR | AdoRx Therapeutics Limited (GB) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020260857-A1 | HYDROXAMATE COMPOUNDS AS ANTAGONISTS OF THE ADENOSINE A2A RECEPTOR | AdoRx Therapeutics Limited (GB) | 2020-12-30 | — | — | WO | disclosed |