Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22833204 | 0.87 | USP2 (0.40) | USP2SMN1; SMN2NR1H2PIK3R1PIK3CA | |
| SCHEMBL22832797 | 0.83 | — | — | |
| SCHEMBL21888789 | 0.80 | NR1H2 (0.44) | USP2SMN1; SMN2NR1H2PIK3R1PIK3CA | |
| SCHEMBL24068402 | 0.78 | USP2 (0.40) | USP2SMN1; SMN2NR1H2PIK3R1PIK3CA | |
| SCHEMBL22833007 | 0.78 | USP2 (0.43) | USP2SMN1; SMN2NR1H2RECQLHTT | |
| SCHEMBL21828586 | 0.77 | NR1H2 (0.42) | USP2SMN1; SMN2NR1H2PIK3R1PIK3CA | |
| SCHEMBL21564361 | 0.76 | USP2 (0.44) | USP2SMN1; SMN2PIK3R1PIK3CARECQL | |
| SCHEMBL22022990 | 0.74 | NR1H2 (0.47) | USP2SMN1; SMN2NR1H2CTSKRECQL | |
| SCHEMBL16340420 | 0.73 | NR1H2 (0.46) | USP2SMN1; SMN2NR1H2CTSKRECQL | |
| SCHEMBL15262928 | 0.73 | NR1H2 (0.46) | USP2SMN1; SMN2NR1H2CTSKRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020260857-A1 | HYDROXAMATE COMPOUNDS AS ANTAGONISTS OF THE ADENOSINE A2A RECEPTOR | AdoRx Therapeutics Limited (GB) | 2020-12-30 | — | — | WO | disclosed |