Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22832929 | 0.84 | — | — | |
| SCHEMBL22118546 | 0.82 | USP2 (0.46) | USP2SMN1; SMN2EPHX2RECQLEPHX1 | |
| SCHEMBL22832999 | 0.78 | USP2 (0.41) | USP2SMN1; SMN2EPHX2RECQLNR1H2 | |
| SCHEMBL14431182 | 0.78 | USP2 (0.44) | USP2SMN1; SMN2EPHX2PKMRECQL | |
| SCHEMBL16566623 | 0.76 | NPSR1 (0.33) | — | |
| SCHEMBL22833204 | 0.74 | USP2 (0.40) | USP2SMN1; SMN2EPHX2RECQLNR1H2 | |
| SCHEMBL17631772 | 0.74 | USP2 (0.45) | USP2SMN1; SMN2EPHX2PKMRECQL | |
| SCHEMBL12373912 | 0.74 | USP2 (0.45) | USP2SMN1; SMN2EPHX2PKMRECQL | |
| SCHEMBL21058295 | 0.73 | NPSR1 (0.39) | — | |
| SCHEMBL22118612 | 0.73 | USP2 (0.43) | USP2SMN1; SMN2EPHX2RECQLEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020260857-A1 | HYDROXAMATE COMPOUNDS AS ANTAGONISTS OF THE ADENOSINE A2A RECEPTOR | AdoRx Therapeutics Limited (GB) | 2020-12-30 | — | — | WO | disclosed |