Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 7/20 | 0.52 |
| ▸ | CDK2 | P24941 | 14/20 | 0.52 |
| ▸ | CDK4 | P11802 | 13/20 | 0.52 |
| ▸ | AURKA | O14965 | 11/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 10/20 | 0.52 |
| ▸ | CDK9 | P50750 | 10/20 | 0.52 |
| ▸ | CDK7 | P50613 | 7/20 | 0.52 |
| ▸ | CDK1 | P06493 | 7/20 | 0.52 |
| ▸ | WEE1 | P30291 | 3/20 | 0.52 |
| ▸ | JAK3 | P52333 | 3/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.52 |
| ▸ | PAK4 | O96013 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.52 |
| ▸ | FYN | P06241 | 2/20 | 0.52 |
| ▸ | CSF1R | P07333 | 2/20 | 0.52 |
| ▸ | RET | P07949 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2286279 | 0.91 | CDK2 (0.51) | JAK2CDK2CDK4AURKAAURKB | |
| SCHEMBL2288421 | 0.90 | CDK2 (0.61) | JAK2CDK2CDK4AURKAAURKB | |
| SCHEMBL2281073 | 0.88 | CDK2 (0.61) | JAK2CDK2CDK4AURKAAURKB | |
| SCHEMBL2286217 | 0.88 | CDK2 (0.59) | JAK2CDK2CDK4AURKAAURKB | |
| SCHEMBL2286403 | 0.85 | JAK2 (0.52) | JAK2CDK2CDK4AURKAAURKB | |
| SCHEMBL2289260 | 0.84 | CDK2 (0.57) | JAK2CDK2CDK4AURKAAURKB | |
| SCHEMBL2282825 | 0.83 | CDK2 (0.49) | JAK2CDK2CDK4AURKAAURKB | |
| SCHEMBL2279493 | 0.83 | CDK2 (0.63) | JAK2CDK2CDK4AURKAAURKB | |
| SCHEMBL2285621 | 0.82 | CDK2 (0.48) | JAK2CDK2CDK4AURKAAURKB | |
| SCHEMBL2282996 | 0.82 | CDK2 (0.48) | JAK2CDK2CDK4AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | JAK2 1056/4885CDK2 2065/4885CDK4 776/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | JAK2 985/4885CDK2 2144/4885CDK4 818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.