Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22833022 | 0.76 | MAPT (0.43) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL6346347 | 0.72 | KMT2A (0.48) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL5529331 | 0.71 | MEN1 (0.69) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL4279649 | 0.70 | MEN1 (0.48) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL19961833 | 0.69 | GAA (0.56) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL3576904 | 0.69 | GAA (0.56) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL14262410 | 0.69 | MEN1 (0.43) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL22833150 | 0.68 | ALDH1A1 (0.43) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL13545621 | 0.67 | GAA (0.69) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL8819539 | 0.67 | TSHR (0.58) | MEN1KMT2AMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020260857-A1 | HYDROXAMATE COMPOUNDS AS ANTAGONISTS OF THE ADENOSINE A2A RECEPTOR | AdoRx Therapeutics Limited (GB) | 2020-12-30 | — | — | WO | disclosed |