SCHEMBL2283374

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2282948	0.88	EGFR (0.64)	KDRFLT1FGFR1EGFRRET
	SCHEMBL2287724	0.88	EGFR (0.64)	KDRFLT1FGFR1EGFRRET
	SCHEMBL2287647	0.86	EGFR (0.77)	KDRFLT1FGFR1EGFRRET
	SCHEMBL1549808	0.85	EGFR (0.78)	KDRFLT1EGFRRETERBB2
	SCHEMBL2286735	0.85	EGFR (0.63)	KDRFLT1FGFR1EGFRRET
	SCHEMBL12376369	0.83	KDR (0.57)	KDRFLT1FGFR1EGFRRET
	SCHEMBL2282023	0.82	ERBB2 (0.66)	KDRFLT1EGFRRETKIF5B
	SCHEMBL2286559	0.82	EGFR (0.78)	KDRFLT1EGFRERBB2EPHB4
	SCHEMBL2282936	0.82	FGFR1 (0.54)	KDRFLT1FGFR1EGFRRET
	SCHEMBL2286835	0.82	FGFR1 (0.54)	KDRFLT1FGFR1EGFRRET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.