SCHEMBL2283785

SCHEMBL2283785

C=CC[Si](CCCC)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3339180 0.92 TSHR (0.41) TSHRALDH1A1
SCHEMBL5420998 0.86 TSHR (0.32) TSHR
SCHEMBL3338322 0.81
SCHEMBL5412372 0.81 TSHR (0.36) TSHRALDH1A1
SCHEMBL10541269 0.81
SCHEMBL6062836 0.78 TSHR (0.37) TSHRALDH1A1
SCHEMBL15302645 0.78 TSHR (0.37) TSHRALDH1A1
SCHEMBL433759 0.78
SCHEMBL109247 0.78 LMNA (0.37) TSHRALDH1A1
SCHEMBL2168996 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356084-B2 POWDER TO HYDROPHOBISE AND ITS USE AKZO NOBEL CHEMICALS INT BV (NL) 2018-05-23 EP disclosed
US-8791221-B2 Addition-curable metallosiloxane compound DAICEL CORPORATION (JP) 2014-07-29 US disclosed
EP-2356084-B1 POWDER TO HYDROPHOBISE AND ITS USE AKZO NOBEL NV (NL) 2014-07-23 EP disclosed
US-8703874-B2 Powder to hydrophobise and its use CELANESE SWITZERLAND AG (CH) 2014-04-22 US disclosed
EP-2650319-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND Daicel Corporation (JP) 2013-10-16 EP disclosed
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND DAICEL CORPORATION (JP) 2013-10-10 US disclosed
US-20110203487-A1 POWDER TO HYDROPHOBISE AND ITS USE AKZO NOBEL N.V. (NL) 2011-08-25 US disclosed
EP-2356084-A1 POWDER TO HYDROPHOBISE AND ITS USE Akzo Nobel N.V. (NL) 2011-08-17 EP disclosed
WO-2010052201-A1 POWDER TO HYDROPHOBISE AND ITS USE AKZO NOBEL N.V. (NL) 2010-05-14 WO disclosed
US-7291567-B2 Silica-based film, method of forming the same, composition for forming insulating film for semiconductor device, interconnect structure, and semiconductor device JSR CORPORATION (JP) 2007-11-06 US disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20060024980-A1 Silica-based film, method of forming the same, composition for forming insulating film for semiconductor device, interconnect structure, and semiconductor device JSR CORPORATION (JP) 2006-02-02 US disclosed
EP-1619226-A1 Silica-based film, method of forming the same, composition for forming insulating film for semiconductor device, interconnect structure, and semiconductor device JSR Corporation (JP) 2006-01-25 EP disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND B2M, MSI2, MNS1 TSHR 4702/4885ALDH1A1 2073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.