Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.63 |
| ▸ | ABHD6 | Q9BV23 | 10/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | PLA2G7 | Q13093 | 7/20 | 0.62 |
| ▸ | FAAH | O00519 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14387748 | 0.90 | MGLL (0.55) | MGLLABHD6CYP2D6PLA2G7FAAH | |
| SCHEMBL15094572 | 0.90 | MGLL (0.57) | MGLLABHD6CYP2D6PLA2G7FAAH | |
| SCHEMBL30272607 | 0.90 | MGLL (0.57) | MGLLABHD6CYP2D6PLA2G7FAAH | |
| SCHEMBL15101007 | 0.90 | MGLL (0.60) | MGLLABHD6CYP2D6PLA2G7FAAH | |
| Piperazine SCHEMBL28324166 | 0.89 | MGLL (0.56) | MGLLABHD6CYP2D6PLA2G7FAAH | |
| SCHEMBL28849570 | 0.87 | MGLL (0.60) | MGLLABHD6CYP2D6PLA2G7FAAH | |
| SCHEMBL28616806 | 0.87 | MGLL (0.60) | MGLLABHD6CYP2D6PLA2G7FAAH | |
| SCHEMBL15093961 | 0.86 | MGLL (0.71) | MGLLABHD6CYP2D6PLA2G7FAAH | |
| SCHEMBL29531253 | 0.86 | MGLL (0.71) | MGLLABHD6CYP2D6PLA2G7FAAH | |
| SCHEMBL17276453 | 0.85 | MGLL (0.70) | MGLLABHD6CYP2D6PLA2G7FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3455226-B1 | SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | LUNDBECK LA JOLLA RESEARCH CENTER INC (US) | 2020-12-30 | — | — | EP | disclosed |