Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22839758 | 1.00 | PLA2G2A (0.45) | PLA2G2APLA2G4AMAPTALDH1A1KDM4E | |
| SCHEMBL29311118 | 0.96 | PLA2G2A (0.45) | PLA2G2APLA2G4AMAPTALDH1A1KDM4E | |
| SCHEMBL26080759 | 0.96 | PLA2G2A (0.44) | PLA2G2APLA2G4AMAPTALDH1A1KDM4E | |
| SCHEMBL27390261 | 0.95 | PLA2G2A (0.44) | PLA2G2APLA2G4AMAPTALDH1A1KDM4E | |
| SCHEMBL27390266 | 0.95 | PLA2G2A (0.44) | PLA2G2APLA2G4AMAPTALDH1A1KDM4E | |
| SCHEMBL29311052 | 0.94 | PLA2G2A (0.46) | PLA2G2APLA2G4AMAPTALDH1A1KDM4E | |
| SCHEMBL15501614 | 0.94 | PLA2G2A (0.45) | PLA2G2APLA2G4AMAPTALDH1A1KDM4E | |
| SCHEMBL22058002 | 0.93 | PLA2G2A (0.43) | PLA2G2APLA2G4AMAPTALDH1A1KDM4E | |
| SCHEMBL27390619 | 0.92 | KMT2A (0.42) | PLA2G2APLA2G4AMAPTALDH1A1KDM4E | |
| SCHEMBL22884400 | 0.92 | PLA2G2A (0.45) | PLA2G2APLA2G4AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3757100-B1 | TRIAZINE COMPOUNDS SUBSTITUTED WITH BULKY GROUPS | NOVALED GMBH (DE) | 2022-12-28 | — | — | EP | disclosed |
| EP-3757100-A1 | TRIAZINE COMPOUNDS SUBSTITUTED WITH BULKY GROUPS | Novaled GmbH (DE) | 2020-12-30 | — | — | EP | disclosed |
| WO-2020260406-A1 | TRIAZINE COMPOUNDS SUBSTITUTED WITH BULKY GROUPS | NOVALED GMBH (DE) | 2020-12-30 | — | — | WO | disclosed |