Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22839857 | 0.88 | ADRB2 (0.42) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL24404580 | 0.84 | ADRB2 (0.41) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL24404476 | 0.83 | ADRB2 (0.42) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL22839839 | 0.82 | ADRB2 (0.40) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL22839941 | 0.82 | ADRB2 (0.43) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL24404439 | 0.82 | ADRB2 (0.41) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL24404494 | 0.81 | ADRB2 (0.43) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL24404553 | 0.81 | ADRB2 (0.43) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL19784429 | 0.80 | ADRB2 (0.39) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL19784426 | 0.80 | ADRB2 (0.47) | ADRB2DRD2DRD1DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484879-B1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-12-30 | — | — | EP | disclosed |