Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.65 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 4/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19770168 | 1.00 | CHRM3 (0.65) | CHRM3NAMPTBCHEACHEMAOB | |
| SCHEMBL19782549 | 0.83 | CHRM3 (0.55) | CHRM3BCHEACHEMAOB | |
| SCHEMBL19770210 | 0.83 | CHRM3 (0.62) | CHRM3BCHEACHEMAOBDRD2 | |
| SCHEMBL31198982 | 0.81 | NAMPT (0.58) | NAMPTGRM5GRM1PDK4HTR6 | |
| SCHEMBL25247422 | 0.81 | ACHE (0.59) | BCHEACHE | |
| SCHEMBL22839957 | 0.80 | CHRM3 (0.71) | CHRM3BCHEACHEMAOBDRD2 | |
| SCHEMBL19770171 | 0.80 | CHRM3 (0.71) | CHRM3BCHEACHEMAOBDRD2 | |
| SCHEMBL19770170 | 0.80 | CHRM3 (0.71) | CHRM3BCHEACHEMAOBDRD2 | |
| SCHEMBL17985816 | 0.78 | CHRM3 (0.64) | CHRM3BCHEACHEDRD2DRD4 | |
| SCHEMBL17985815 | 0.78 | CHRM3 (0.64) | CHRM3BCHEACHEDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484879-B1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-12-30 | — | — | EP | disclosed |