Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11984370 | 0.90 | TDP1 (0.37) | TDP1SLC6A5KDM4AHIF1ATET2 | |
| SCHEMBL4331941 | 0.90 | TDP1 (0.37) | TDP1SLC6A5KDM4AHIF1ATET2 | |
| SCHEMBL19519807 | 0.87 | TDP1 (0.44) | TDP1SLC6A5KDM4AHIF1ATET2 | |
| SCHEMBL23780008 | 0.85 | EPHX2 (0.38) | TDP1SLC6A5KDM4AHIF1ATET2 | |
| SCHEMBL23780010 | 0.85 | EPHX2 (0.38) | TDP1SLC6A5KDM4AHIF1ATET2 | |
| SCHEMBL22840058 | 0.81 | TDP1 (0.44) | TDP1FOLH1ITGB3ITGA2BCPB2 | |
| SCHEMBL20274554 | 0.81 | TDP1 (0.44) | TDP1FOLH1ITGB3ITGA2BCPB2 | |
| SCHEMBL16010862 | 0.81 | FOLH1 (0.41) | TDP1SLC6A5FOLH1ITGB3ITGA2B | |
| SCHEMBL16010863 | 0.81 | FOLH1 (0.41) | TDP1SLC6A5FOLH1ITGB3ITGA2B | |
| SCHEMBL18396048 | 0.81 | FOLH1 (0.41) | TDP1SLC6A5FOLH1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3335736-B1 | HETERODIMERS OF GLUTAMIC ACID | MOLECULAR INSIGHT PHARM INC (US) | 2020-12-30 | — | — | EP | disclosed |