Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.56 |
| ▸ | CDK2 | P24941 | 8/20 | 0.56 |
| ▸ | CDK1 | P06493 | 5/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.56 |
| ▸ | CDK9 | P50750 | 5/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.56 |
| ▸ | CDK7 | P50613 | 4/20 | 0.56 |
| ▸ | CCNH | P51946 | 4/20 | 0.56 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.55 |
| ▸ | GSK3B | P49841 | 3/20 | 0.55 |
| ▸ | AURKA | O14965 | 2/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | JAK2 | O60674 | 2/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.55 |
| ▸ | CDC7 | O00311 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2282398 | 0.89 | CDK2 (0.58) | PIK3CGPIK3CAPIK3CBCDK2CDK1 | |
| SCHEMBL2281760 | 0.87 | CDK2 (0.58) | PIK3CGPIK3CAPIK3CBCDK2CDK1 | |
| SCHEMBL2283789 | 0.85 | CDK2 (0.58) | CDK2CDK1CCNT1CCNA2CDK9 | |
| SCHEMBL2285781 | 0.85 | CDK2 (0.67) | PIK3CGPIK3CAPIK3CBCDK2CDK1 | |
| SCHEMBL27741280 | 0.84 | CDK2 (0.55) | CDK2CDK1CCNT1CCNA2CDK9 | |
| SCHEMBL2283318 | 0.83 | MKNK2 (0.52) | CDK2CDK1CCNT1CCNA2CDK9 | |
| SCHEMBL2285679 | 0.83 | CDK2 (0.58) | PIK3CGPIK3CAPIK3CBCDK2CDK1 | |
| SCHEMBL2281574 | 0.83 | CDK2 (0.60) | PIK3CGPIK3CAPIK3CBCDK2CDK1 | |
| SCHEMBL2286766 | 0.83 | CDK2 (0.55) | PIK3CGPIK3CAPIK3CBCDK2CDK1 | |
| SCHEMBL2282373 | 0.81 | CDK2 (0.53) | PIK3CGPIK3CAPIK3CBCDK2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
| CN-101309586-A | Thiazole compounds as fungicides | BAYER CROPSCIENCE AG (DE) | 2008-11-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | PIK3CG 4241/4885PIK3CA 3293/4885PIK3CB 4206/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | PIK3CG 4256/4885PIK3CA 3359/4885PIK3CB 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.