SCHEMBL2284148

SCHEMBL2284148

C=CC[SiH2]OC(COCCCC)OCCCC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 1/20 0.33
LPAR1 Q92633 4/20 0.31
LPAR3 Q9UBY5 4/20 0.31
LPAR2 Q9HBW0 1/20 0.31
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2282170 0.87 TDP1 (0.36)
SCHEMBL2282798 0.86 TSHR (0.32)
SCHEMBL2286752 0.78 TSHR (0.32)
SCHEMBL9502490 0.75 TSHR (0.42) LPAR1LPAR3LPAR2USP2
SCHEMBL3300650 0.72 USP2 (0.36) LPAR1LPAR3LPAR2USP2
SCHEMBL2285864 0.72
SCHEMBL15309363 0.72
SCHEMBL582639 0.71 LPAR1 (0.37) LPAR1LPAR3LPAR2USP2
SCHEMBL28756178 0.70 CA1 (0.36) PLA2G2C
SCHEMBL28348882 0.69 TSHR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703874-B2 Powder to hydrophobise and its use CELANESE SWITZERLAND AG (CH) 2014-04-22 US disclosed
US-20110203487-A1 POWDER TO HYDROPHOBISE AND ITS USE AKZO NOBEL N.V. (NL) 2011-08-25 US disclosed