SCHEMBL2284150

SCHEMBL2284150

C=CC[SiH2]OC(C)(OCCCC)OCCCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
HPGD P15428 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2282174 0.89
SCHEMBL2282800 0.81 TSHR (0.31) TSHRHPGDALDH1A1
SCHEMBL15309363 0.72
SCHEMBL1229674 0.72
SCHEMBL10762136 0.71 TSHR (0.44) TSHRHPGDALDH1A1
SCHEMBL5574616 0.69
SCHEMBL5573911 0.69
SCHEMBL5570782 0.69
SCHEMBL5574597 0.69 ALDH1A1 (0.35) TSHRALDH1A1
SCHEMBL2286295 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703874-B2 Powder to hydrophobise and its use CELANESE SWITZERLAND AG (CH) 2014-04-22 US disclosed
US-20110203487-A1 POWDER TO HYDROPHOBISE AND ITS USE AKZO NOBEL N.V. (NL) 2011-08-25 US disclosed