SCHEMBL2284348

SCHEMBL2284348

CC(N)(C#N)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15837116 0.78
Hydrochloric Acid SCHEMBL16446299 0.76
SCHEMBL15837127 0.74
SCHEMBL1880617 0.73
Hydrochloric Acid SCHEMBL16446453 0.72
SCHEMBL26874463 0.72
SCHEMBL15776833 0.71
SCHEMBL534716 0.71
Hydrochloric Acid SCHEMBL11251317 0.71
SCHEMBL19629045 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662185-B2 Amino-substituted imidazo[1,2-A] pyridinecarboxamides and their use BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2020-05-26 US disclosed
US-10662185-B2 Amino-substituted imidazo[1,2-A] pyridinecarboxamides and their use BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2020-05-26 US disclosed
US-20190248783-A9 AMINO-SUBSTITUTED IMIDAZO[1,2-A] PYRIDINECARBOXAMIDES AND THEIR USE BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2019-08-15 US disclosed
US-20190248783-A9 AMINO-SUBSTITUTED IMIDAZO[1,2-A] PYRIDINECARBOXAMIDES AND THEIR USE BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2019-08-15 US disclosed
US-20180319794-A1 AMINO-SUBSTITUTED IMIDAZO[1,2-A] PYRIDINECARBOXAMIDES AND THEIR USE BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-11-08 US disclosed
US-10052312-B2 Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-08-21 US disclosed
EP-3272749-A1 AMINO-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINECARBOXAMIDES AND THEIR USE AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE Bayer Pharma Aktiengesellschaft (DE) 2018-01-24 EP disclosed
EP-3030562-B1 SUBSTITUTED PYRAZOLO[1,5-A]-PYRIDINE-3-CARBOXAMIDES AND USE THEREOF Bayer Pharma AG (DE) 2017-07-26 EP disclosed
EP-3030562-B1 SUBSTITUTED PYRAZOLO[1,5-A]-PYRIDINE-3-CARBOXAMIDES AND USE THEREOF Bayer Pharma AG (DE) 2017-07-26 EP disclosed
US-20170182014-A1 AMINO-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINECARBOXAMIDES AND THEIR USE BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-06-29 US disclosed
US-20090240041-A1 TUMOR IMAGING COMPOUNDS EMORY UNIVERSITY (US) 2009-09-24 US disclosed
US-20090240041-A1 TUMOR IMAGING COMPOUNDS EMORY UNIVERSITY (US) 2009-09-24 US disclosed
WO-2009087098-A2 QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-07-16 WO disclosed
US-7544715-B2 Tumor imaging compounds EMORY UNIVERSITY (US) 2009-06-09 US disclosed
US-7544715-B2 Tumor imaging compounds EMORY UNIVERSITY (US) 2009-06-09 US disclosed
US-7544715-B2 Tumor imaging compounds EMORY UNIVERSITY (US) 2009-06-09 US disclosed
EP-1499584-A4 TUMOR IMAGING COMPOUNDS UNIV EMORY (US) 2007-08-15 EP disclosed
US-20050192458-A1 radiolabeled amino acids for use as metabolic tracers to image tumors using positron emission tomography; combine the advantageous properties of alpha -aminoisobutyric acid analogs namely, their rapid uptake and prolonged retention in tumors with the properties of halogen sustituents EMORY UNIVERSITY 2005-09-01 US disclosed
EP-1499584-A2 TUMOR IMAGING COMPOUNDS Emory University (US) 2005-01-26 EP disclosed
WO-2003093412-A2 TUMOR IMAGING COMPOUNDS EMORY UNIVERSITY (US) 2003-11-13 WO disclosed