Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 12/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.35 |
| ▸ | AHCY | P23526 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22843546 | 0.75 | NT5E (0.47) | NT5E | |
| SCHEMBL22843523 | 0.73 | ENPP1 (0.48) | NT5EENPP1PLCG1 | |
| SCHEMBL22843633 | 0.72 | NT5E (0.40) | NT5E | |
| SCHEMBL24078966 | 0.70 | NT5E (0.50) | NT5EENPP1AHCYPLCG1 | |
| SCHEMBL22843518 | 0.69 | NT5E (0.45) | NT5E | |
| SCHEMBL22843677 | 0.69 | NT5E (0.54) | NT5E | |
| SCHEMBL22843632 | 0.69 | NT5E (0.54) | NT5E | |
| SCHEMBL22843662 | 0.69 | ADORA3 (0.41) | NT5E | |
| SCHEMBL22843535 | 0.69 | PDE1A (0.35) | NT5EENPP1 | |
| SCHEMBL19370193 | 0.62 | ENPP1 (0.49) | NT5EENPP1PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200405629-A1 | PARENTERALLY ADMINISTERED IMMUNE ENHANCING DRUGS | ARCUS BIOSCIENCES, INC. | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200405629-A1 | PARENTERALLY ADMINISTERED IMMUNE ENHANCING DRUGS | NT5C2, ADA, ENTPD1 | NT5E 10/4885ENPP1 6/4885AHCY 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.