Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | OTC | P00480 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 8/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24838646 | 0.97 | GSR (0.47) | GSROTCGLP1RGNAI3GNAO1 | |
| SCHEMBL19135682 | 0.90 | GLP1R (0.51) | GSROTCGLP1RNOD1DDAH1 | |
| SCHEMBL24470266 | 0.88 | GLP1R (0.48) | OTCGLP1RNOD1DDAH1 | |
| SCHEMBL19801989 | 0.88 | GLP1R (0.45) | OTCGLP1RNOD1 | |
| SCHEMBL24788157 | 0.88 | OTC (0.47) | GSROTCGLP1RNOD1DDAH1 | |
| SCHEMBL24788148 | 0.88 | GLP1R (0.50) | OTCGLP1RGNAI3GNAO1GNAI1 | |
| SCHEMBL24788082 | 0.88 | GLP1R (0.45) | GSROTCGLP1RNOD1DDAH1 | |
| SCHEMBL19599417 | 0.88 | GLP1R (0.42) | GSROTCGLP1RNOD1 | |
| SCHEMBL19599351 | 0.88 | GLP1R (0.42) | GSROTCGLP1RNOD1 | |
| SCHEMBL19599416 | 0.88 | GLP1R (0.42) | GSROTCGLP1RNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200407409-A1 | EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS | CHEN JIANHE (CN) | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407409-A1 | EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS | EGFR, LDLR, FFAR2 | GSR 1765/4885OTC 4147/4885GLP1R 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.