Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531130 | 0.94 | SMN1; SMN2 (0.51) | HDAC3HDAC1CA2SMN1; SMN2HPGD | |
| SCHEMBL22845020 | 0.89 | HDAC3 (0.48) | HDAC3HDAC1CA2SMN1; SMN2HPGD | |
| SCHEMBL22845092 | 0.89 | HDAC3 (0.46) | HDAC3HDAC1CA2SMN1; SMN2HPGD | |
| SCHEMBL22845012 | 0.83 | SMN1; SMN2 (0.41) | HDAC3HDAC1CA2SMN1; SMN2HPGD | |
| SCHEMBL29531296 | 0.83 | SMN1; SMN2 (0.41) | HDAC3HDAC1CA2SMN1; SMN2HPGD | |
| SCHEMBL22844929 | 0.81 | SMN1; SMN2 (0.46) | HDAC3HDAC1CA2SMN1; SMN2HPGD | |
| SCHEMBL21142116 | 0.77 | SMN1; SMN2 (0.66) | HDAC3HDAC1CA2SMN1; SMN2HPGD | |
| SCHEMBL14386036 | 0.74 | SMN1; SMN2 (0.61) | HDAC3HDAC1CA2SMN1; SMN2HPGD | |
| SCHEMBL29531265 | 0.74 | SMN1; SMN2 (0.41) | HDAC3HDAC1CA2SMN1; SMN2HPGD | |
| SCHEMBL29872250 | 0.74 | SMN1; SMN2 (0.41) | HDAC3HDAC1CA2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020260514-A1 | BIS(2-HALOACETAMIDO)-COMPOUNDS FOR USE AS LINKING AGENTS AND RESULTANT PRODUCTS WHICH COMPRISE ANTIBODIES, HALF-ANTIBODIES AND ANTIBODY FRAGMENTS | THE UNIVERSITY OF BATH (GB) | 2020-12-30 | — | — | WO | disclosed |