Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531296 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2CRBNHDAC1HDAC3CA2 | |
| SCHEMBL29872250 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2CRBNHDAC1HDAC3CA2 | |
| SCHEMBL22833140 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2CRBNHDAC1HDAC3CA2 | |
| SCHEMBL22845091 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2CRBNHDAC1HDAC3CA2 | |
| SCHEMBL29531265 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2CRBNHDAC1HDAC3CA2 | |
| SCHEMBL29531130 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2HDAC1HDAC3CA2HPGD | |
| SCHEMBL29531490 | 0.83 | CRBN (0.41) | SMN1; SMN2CRBNHDAC1HDAC3CA2 | |
| SCHEMBL22845010 | 0.83 | HDAC3 (0.47) | SMN1; SMN2HDAC1HDAC3CA2HPGD | |
| SCHEMBL29531240 | 0.81 | CRBN (0.42) | SMN1; SMN2CRBNCA2ALDH1A1HTT | |
| SCHEMBL13698906 | 0.78 | NPC1 (0.56) | SMN1; SMN2CRBNHDAC1HDAC3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020260514-A1 | BIS(2-HALOACETAMIDO)-COMPOUNDS FOR USE AS LINKING AGENTS AND RESULTANT PRODUCTS WHICH COMPRISE ANTIBODIES, HALF-ANTIBODIES AND ANTIBODY FRAGMENTS | THE UNIVERSITY OF BATH (GB) | 2020-12-30 | — | — | WO | disclosed |